HYPERHIDROSIS SCIENCE: Hyperhydrosis research, treatments - excessive sweating knowledge
DR. STOLL'S HYPERHIDROSIS ARTICLE INDEX
- Is previous throacic sympathectomy a risk factor for exertion?
- Treatment of palmar hyperhidrosis: T(4) level compared with T(2) and T(3).
- Severe Pomphylox Following Endoscopic Thoracic Sympathectomy for Hyperhidrosis
- Repeat Liposuction-Curettage Treatment of Axillary Hyperhidrosis Effectiveness
- Contralateral Hyperhidrosis After Intracerebral Hemmorage
- Facial hyperhidrosis: Best Practice Recommendations and Special Considerations.
- Outpatient Microthoraacosopic Sympathectomy for Palmar Hyperhidrosis
- Use of Oral Glycopyrronium in Hyperhidrosis
- Oxybutynin for Patients with Hyperhidrosis in One Case Study
- Paroxetine Useful for Palmar-Plantar Hyperhidrosis in One Case Study
- Thoracic Sympathicolysis for Primary Hyperhydrosis
- Improved Quality of Life After Sympathetic Block for Upper limb Hyperhidrosis.
- Surgical Treatment of Axillary Hyperhidrosis
- Mydriasis and Accommodative Failure from Exposure to Topical Glycopyrrolate Used in Hyperhydrosis.
- Facial Hyperhydrosis-Induced Social Fear Alleviated with Topiramate.
- Treatment of Inguinal Hyperhidrosis or HH with Botulinum Toxin Type A.
- Hyperhidrosis in Parkinson's Disease.
- Hyperhydrosis: A Few and Often Early Symptom in Fabry Disease.
HYPERHIDROSIS KNOWLEDGE AND SCIENCE
JUNE 2006: Sweating associated with diseases
Medical Publication:
Hyperhidrosis in Parkinson's disease.
Moving Disorders, 2006.
Synopsis: 50 patients with Parkinson's disease were studied. 13 of them complained of excessive sweating, while the other 37 had no sweating problems.
A scientific device measured the skin's sweating response to electrical stimulation of the palms. It was determined that the patients who originally complained of excessive sweating had decreased sweating in response to electrical stimulation, versus those who never complained of excessive sweating. The authors, although somewhat puzzled by the results, theorized that increased underarm sweating could be a compensatory phenomenon for reduced sweating in the palms.
Conclusion: This interesting study illustrates a truism of medical scientific research. Sometimes, the results that you get are contrary to what you would expect. The authors fully expected that those people who had excessive sweating on their bodies would have hightened sweating to electrical stimuli on their palms. Instead, the opposite was true. What does a scientist do when the results conflict with the original theory? They try to figure out why things "went wrong". In this case, they felt that a reduction in sympathetic nerve function in the extremities was compensated for by and increase in sympathetic nerve function elsewhere.
This raises several interesting questions. Do people who sweat more in their armpits generally sweat less on their palms? Usually not. Why then would the authors raise the issue of compensatory hyperhidrosis in this instance? Perhaps patients with Parkinson's disease sweat differently than people without Parkinson's disease. Or perhaps they sweat more than unaffected individuals. In this study, 13 of 50 people with Parkinson's disease had excessive sweating problems. That is 26%, which is higher than the general population. Is this percentage reflective of the general Parkinson's population or does this small sample of Parkinson's patients have a higher rate of hyperhidrosis? Often, medical studies raise more questions than they answer, especially with hyperhidrosis.
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